Here're some places I've picked out for my home city, (not hometown) Rochester (warning: most are probably boring history things). [Links too long, forced to use t9k.me]
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https://t9k.me/1Dp : Susan B. Anthony House
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https://t9k.me/1Dq : Natl. Museum of Play
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https://t9k.me/1Dr : G. Eastman House (Kodak)
> Also, Niagara Falls.
Even if you don't film someone (or yourself) riding the falls in a barrel, just go there anyway. It's not a trap at all. :3
I see St. Louis in there.
> Gateway Arch, definitely.
> Also, Budweiser.
Americans like beer, no question.
http://www.budweisertours.com/z01/
Still sitting in New York?
> Head to Manhattan!
Statue of Liberty, Empire State Building, Times^2 (cwutididther), motha-f**kin' Yankee Stadium (the new one :/ )...
Lastly, make sure you stop at
> the Continental Divide.
I still remember when I stopped there with my uncle. Ask me about it sometime, it's not much of a tale. xD